The mutant protein were found to possess higher bioactivity than native standard protein 檢測改構(gòu)后之hbfgf蛋白活性高于未改構(gòu)蛋白。
The mutant protein of huntington ' s attacks the railroad system of brain cells and impairs transport of essential materials required for neurons to function 突變的亨廷頓蛋白攻擊腦內(nèi)細胞的轉(zhuǎn)運系統(tǒng),繼而損害了神經(jīng)元要發(fā)揮正常功能所必需的物質(zhì)的轉(zhuǎn)運。
Western - blot result indicated that the protein could bind to anti - br antibody specifically . thus , a br mutant ( tyr79 - ? rg ) was successively conducted . the mutant protein was also analysesed by some bioinfomnatic software 通過觀察各種br的突變蛋白在結(jié)構(gòu)和光學性能上的變化,從而確定br結(jié)構(gòu)和功能上的關(guān)鍵氨基酸,使我們更深入得了解蛋白質(zhì)結(jié)構(gòu)和功能之間的關(guān)系。